Aging-Research/Biochemistry Lab.
Home Professor Lab. members Publications Lectures Aging/Anti-aging

Professor

  1. CV, 한글
    성 명 정 해 영(鄭 海 泳)(Chung Hae Young)

    주 소 부산광역시 금정구 부산대학로 63번길 2(장전동)
    부산대학교 약학대학 436호 생화학연구실
    051-510-2814
    핸드폰 010-6532-1569
       

    ○ 학력 및 경력, 학회활동

    1980. 2 : 부산대학교 약학대학 학사

    1982. 2 : 서울대학교 약학대학원 석사

    1988. 2 : 일본 도야마의약학대학 박사

    1995. 2 : 미국 텍사스대학교 박사후연구원

    2011.01 ~ 2011.12 : (사)한국노화학회 회장

    1989.04 ~ 현 재 : 부산대학교 약학대학 - 교수

    2000.09 ~ 현 재 : 노화조직은행 - 은행장

    2006.04 ~ 현 재 : 과학기술 한림원 - 정회원

    2009.09 ~ 현 재 : 분자염증 노화제어 연구센터 - 센터장

    ○ 수상경력

    2007 부산대학교 우수 연구자

    2008 부산대학교 최우수 연구자

    2010 부산대학교 우수 연구자

    2012 부산대학교 우수 연구자

    2014 부산과학기술상

    2015 보건복지부 장관상 (고령친화산업육성 유공)

    ○ 관심 연구 분야

    - 노화의 분자기전

    - 노화제어 물질 발굴 및 작용기전

    - 피부노화 및 혈관노화 제어기전

    ○ 최근 대표 논문

    1) Chung KW, Kim KM, Choi YJ, An HJ, Lee B, Kim DH, Lee EK, Im E, Lee J, Im DS, Yu BP, Chung HY : The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Autophagy, (2017, in press)

    2) Lee EK, Chung KW, Kim YR, HA SG, Kim DH, Jung KJ, Lee B, Im E, Yu BP, Chung HY : Small RNA induce the activation of the pro-inflammatory RLR7 signaling pathway in aged rat Kidneys. Aging Cell, (2017, in press).

    3) Kim SM, Lee B, An HJ, Kim DH, Park KC, Noh SG, Chung KW, Lee EK, Kim KM, Kim DH, Kim SJ, Chun P, Lee HJ, Moon HR, Chung HY : Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget, (2017, in press).

    4) An HJ, Lee B, Kim DH, Lee EK, Chung KW, Park MH, Jeong HO, Kim SM, Moon KM, Kim YR, Kim SJ, Yun HY, Chun P, Yu BP, Moon HR, Chung HY : Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013). Oncotarget, 8(10),16912-16924 (2017).

    5) Chung KW, Jeong HO, Lee B, Park D, Kim DH, Choi YJ, Lee EK, Kim KM, Park JW, Yu BP, Chung HY : Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis. Oncotarget, 8(5),7315-7327 (2017).

    6) Kim, CH, Lee EK, Choi YJ, An HJ, Chung HO, Park DE, Ghim BC., Yu BP, Back J, Chung HY : Short-term calorie restriction ameliorates genomewide, age-related alterations in DNA methylation. Aging Cell, (2016, in press).

    7) Choi YJ, Moon KM, Chung KW, Jeong JW, Park D, Kim DH, Yu BP, Chung HY : The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging. Oncotarget, 7(33),52685-52694 (2016).

    8) Park D, Kim BC, Kim CH, Choi YJ, Jeong HO, Kim ME, Lee JS, Park MH, Chung KW, Kim DH, Lee J, Im DS, Yoon S, Lee S, Yu BP, Bhak J, Chung HY : RNA-Seq analysis reveals new evidence for Inflammation-related changes in aged kidney, Oncotarget, 7(21),30037-30048 (2016).

    9) Chung KW., Lee EK, Kim DH, An HJ, Kim ND, Im DS, Lee JW, Yu BP, Chung HY : Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/1L-1 for steatohepatitis, Aging Cell,14(4), 524-533 (2015).

    10) Chung KW, Choi YJ, Park MH, Jang EJ, Kim DH, Park BH, Yu BP, Chung HY : Molecular Insights into SIRT1 Protection Against UVB-Induced Skin Fibroblast Senescence by Suppression of Oxidative Stress and p53 Acetylation, J Gerontol A Biol Sci Med Sci, 70(8), 959-968 (2015).


  2. CV, English

    Hae Young Chung, Ph.D.
    Education and Training
    1994 - 1995 Post-Doc. in Gerontology
    University of Texas Health Science Center, Texas, U.S.A.
    1984 - 1988 Ph.D. in Biochemistry
    Toyama University, Toyama, Japan
    1980 - 1982 M.S. in Pharmacology
    Seoul National University, Seoul, Korea
    1976 - 1980 B.S. in Pharmacy
    Pusan National University, Busan, Korea
    Professional Experiences
    2009.9 - Present Director
    Molecular Inflammation Research Center for Aging Intervention (MRCA), Busan, Korea
    2006.12 - Present Member of Korean Academy of Science and Technology, Korea
    1989.4 - Present Professor
    Department of Pharmacy,
    College of Pharmacy Pusan National University, Busan, Korea
    2011.1 - 2011.12 President
    The Korean Society for Gerontology, Korea
    2004.3 - 2006.2 Dean
    College of Pharmacy, Pusan National University, Busan, Korea

    Recent selected publications

    1) Chung KW, Kim KM, Choi YJ, An HJ, Lee B, Kim DH, Lee EK, Im E, Lee J, Im DS, Yu BP, Chung HY : The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Autophagy, (2017, in press)

    2) Lee EK, Chung KW, Kim YR, HA SG, Kim DH, Jung KJ, Lee B, Im E, Yu BP, Chung HY : Small RNA induce the activation of the pro-inflammatory RLR7 signaling pathway in aged rat Kidneys. Aging Cell, (2017, in press).

    3) Kim SM, Lee B, An HJ, Kim DH, Park KC, Noh SG, Chung KW, Lee EK, Kim KM, Kim DH, Kim SJ, Chun P, Lee HJ, Moon HR, Chung HY : Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. Oncotarget, (2017, in press).

    4) An HJ, Lee B, Kim DH, Lee EK, Chung KW, Park MH, Jeong HO, Kim SM, Moon KM, Kim YR, Kim SJ, Yun HY, Chun P, Yu BP, Moon HR, Chung HY : Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013). Oncotarget, 8(10),16912-16924 (2017).

    5) Chung KW, Jeong HO, Lee B, Park D, Kim DH, Choi YJ, Lee EK, Kim KM, Park JW, Yu BP, Chung HY : Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis. Oncotarget, 8(5),7315-7327 (2017).

    6) Kim, CH, Lee EK, Choi YJ, An HJ, Chung HO, Park DE, Ghim BC., Yu BP, Back J, Chung HY : Short-term calorie restriction ameliorates genomewide, age-related alterations in DNA methylation. Aging Cell, (2016, in press).

    7) Choi YJ, Moon KM, Chung KW, Jeong JW, Park D, Kim DH, Yu BP, Chung HY : The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging. Oncotarget, 7(33),52685-52694 (2016).

    8) Park D, Kim BC, Kim CH, Choi YJ, Jeong HO, Kim ME, Lee JS, Park MH, Chung KW, Kim DH, Lee J, Im DS, Yoon S, Lee S, Yu BP, Bhak J, Chung HY : RNA-Seq analysis reveals new evidence for Inflammation-related changes in aged kidney, Oncotarget, 7(21),30037-30048 (2016).

    9) Chung KW., Lee EK, Kim DH, An HJ, Kim ND, Im DS, Lee JW, Yu BP, Chung HY : Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/1L-1 for steatohepatitis, Aging Cell,14(4), 524-533 (2015).

    10) Chung KW, Choi YJ, Park MH, Jang EJ, Kim DH, Park BH, Yu BP, Chung HY : Molecular Insights into SIRT1 Protection Against UVB-Induced Skin Fibroblast Senescence by Suppression of Oxidative Stress and p53 Acetylation, J Gerontol A Biol Sci Med Sci, 70(8), 959-968 (2015).

부산광역시 금정구 부산대학로 63번길 2(장전동)

부산대학교 약학대학 약학연구동

Tel: 051-510-2814. Fax: 051-518-2821